How to build a complex dendrite arbors? Novel roles of myosin in dendrite branching
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چکیده
منابع مشابه
Increased dendrite branching in AbetaPP/PS1 mice and elongation of dendrite arbors by fasudil administration.
Amyloid-beta (Abeta) overproduction and dendrite arbor atrophy are hallmarks of Alzheimer's disease. The RhoA GTPase (Rho) signals through Rho kinase (ROCK) to control cytoskeletal dynamics and regulate neuron structure. Hyperactive Rho signaling destabilizes neurons leading to dendritic regression that can be rescued by genetic or pharmacological reduction of ROCK signaling. To understand what...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2016
ISSN: 1662-5102
DOI: 10.3389/conf.fncel.2016.36.00064